The PBXIP1 Polyclonal Antibody (CAB8790) is a valuable tool for researchers studying PBXIP1, a protein involved in various cellular processes including cell proliferation and differentiation. This antibody, generated in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By targeting the PBXIP1 protein, this antibody allows for the detection and analysis of PBXIP1 levels in different cell types, making it an ideal choice for studies in cell biology and cancer research.PBXIP1 plays a critical role in cellular pathways that contribute to tumor development and progression, making it a potential target for therapeutic intervention in cancer treatment.
By understanding the function of PBXIP1, researchers can gain insights into the mechanisms underlying cancer growth and potentially identify new therapeutic targets for drug development. The PBXIP1 Polyclonal Antibody is a reliable tool for investigating the role of PBXIP1 in cancer biology and exploring its potential as a therapeutic target.
Product Name:
PBXIP1 Rabbit Polyclonal Antibody
SKU:
CAB8790
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PBXIP1 (NP_065385.2).
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.
Purification Method:
Affinity purification
Gene ID:
57326
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PBXIP1 antibody (CAB8790) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
