The PBX3 Polyclonal Antibody (CAB17514) is a valuable tool for researchers studying PBX3, a transcription factor involved in developmental processes and oncogenesis. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PBX3 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential component for studies in developmental biology and cancer research.PBX3, belonging to the TALE (three-amino acid loop extension) family of homeodomain proteins, plays a crucial role in the regulation of gene expression and cell differentiation.
Its involvement in various cellular processes makes it a target of interest for researchers investigating developmental disorders, cancer progression, and genetic abnormalities. Understanding the function of PBX3 is essential for advancing our knowledge of these conditions and identifying potential therapeutic targets for intervention.
Product Name:
PBX3 Rabbit Polyclonal Antibody
SKU:
CAB17514
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PBX3 (NP_006186.1).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in animal organ development; neuron development; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including adult locomotory behavior; dorsal spinal cord development; and regulation of respiratory gaseous exchange by nervous system process. Predicted to be located in nucleus. Predicted to be part of chromatin.
Purification Method:
Affinity purification
Gene ID:
5090
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PBX3 Rabbit pAb (CAB17514) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
