The Paxillin Rabbit Monoclonal Antibody (CAB19100) is a versatile tool for researchers interested in studying paxillin, a focal adhesion protein that plays a crucial role in cell migration and signaling. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards paxillin in human samples, making it an ideal choice for Western blotting experiments. By binding to paxillin, this antibody enables accurate detection and analysis of paxillin levels in various cell types.Paxillin is a key player in cell adhesion and migration processes, making it an important target for studies in cancer metastasis, developmental biology, and tissue remodeling.
Its intricate involvement in cell signaling pathways also positions paxillin as a potential therapeutic target for conditions like cancer and fibrosis. By utilizing the Paxillin Rabbit Monoclonal Antibody, researchers can gain valuable insights into the functions and regulation of paxillin, advancing our understanding of its role in health and disease.
Product Name:
Paxillin Rabbit Monoclonal Antibody
SKU:
CAB19100
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Paxillin (P49023).
This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
Purification Method:
Affinity purification
Gene ID:
5829
Clone Number:
ARC0368
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Paxillin antibody (CAB19100) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
