The Pax7 Polyclonal Antibody (CAB7335) is a valuable tool for researchers studying Pax7, a transcription factor crucial for muscle development and regeneration. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in immunofluorescence and immunohistochemistry applications.Pax7 is a key regulator of muscle satellite cells, which are responsible for muscle repair and growth. Studies have shown that Pax7 plays a pivotal role in muscle regeneration after injury and in maintaining muscle stem cell populations.
Dysregulation of Pax7 has been implicated in muscle diseases and disorders, making it an important target for research in muscle biology and regenerative medicine.By using the Pax7 Polyclonal Antibody, researchers can visualize and analyze Pax7 expression in various tissue samples, providing valuable insights into its role in muscle development and regeneration. This antibody is an essential tool for advancing our understanding of Pax7 function and its implications for muscle health and disease.
Product Name:
PAX7 Rabbit Polyclonal Antibody
SKU:
CAB7335
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human PAX7 (NP_039236.1).
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5081
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using PAX7 Rabbit pAb (CAB7335) at 1:400 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 30s.
