The Pax4 Polyclonal Antibody (CAB5414) is a crucial tool for researchers studying the Pax4 protein, which plays a key role in pancreatic development and beta cell function. This antibody, produced in rabbits, is specifically designed for use in detecting Pax4 in human samples and has been validated for Western blot applications.Pax4 is a transcription factor that is essential for the development and function of insulin-producing beta cells in the pancreas. Dysregulation of Pax4 has been linked to pancreatic disorders and diabetes, making it an important target for research in these areas.
The Pax4 Polyclonal Antibody binds specifically to Pax4, allowing for accurate detection and analysis in a variety of cell types.By using the Pax4 Polyclonal Antibody, researchers can gain valuable insights into the role of Pax4 in pancreatic development and function, as well as its potential as a therapeutic target for diabetes and other related conditions. This antibody is a valuable tool for studying the mechanisms underlying pancreatic disorders and may lead to the development of novel treatments in the future.
Product Name:
PAX4 Rabbit Polyclonal Antibody
SKU:
CAB5414
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-200 of human PAX4 (NP_006184.2).
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
Purification Method:
Affinity purification
Gene ID:
5078
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Lovo cells, using PAX4 antibody (CAB5414) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
