The Pax3 Polyclonal Antibody (CAB1675) is a valuable tool for researchers studying the Pax3 protein, a key regulator of embryonic development and stem cell differentiation. This antibody is raised in rabbits and has been validated for use in Western blot applications, providing reliable detection and analysis of Pax3 in various cell types.Pax3 is known for its role in neural crest development, muscle development, and melanocyte differentiation, making it a crucial target for investigation in developmental biology and regenerative medicine research. By targeting Pax3 with this antibody, researchers can gain insights into its functions and pathways, ultimately leading to a better understanding of its role in tissue regeneration, disease progression, and potential therapeutic applications.
The Pax3 Polyclonal Antibody is highly specific for human samples and offers strong reactivity, making it an excellent choice for studies focused on the intricacies of Pax3-mediated processes. With its versatility and reliability, this antibody is a valuable asset for researchers seeking to unravel the complexities of developmental biology and stem cell biology.
Product Name:
PAX3 Rabbit Polyclonal Antibody
SKU:
CAB1675
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human PAX3 (NP_852122.1).
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Purification Method:
Affinity purification
Gene ID:
5077
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PAX3 Rabbit pAb (CAB1675) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
