PAX3 Polyclonal Antibody (CAB21524)
- SKU:
- CAB21524
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
Frequently bought together:
Description
Product Name: | PAX3 Polyclonal Antibody |
SKU: | CAB21524 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 341-479 of human PAX3 (NP_852122.1). |
Sequence: | QSTI PSNP DSSS AYCL PSTR HGFS SYTD SFVP PSGP SNPM NPTI GNGL SPQV MGLL TNHG GVPH QPQT DYAL SPLT GGLE PTTT VSAS CSQR LDHM KSLD SLPT SQSY CPPT YSTT GYSM DPVT GYQY GQYG QSKP WTF |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | WS1; WS3; CDHS; HUP2; PAX-3; PAX3 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 53kDa |
Observed MW: | Refer to figures |
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Purification Method: | Affinity purification |
Gene ID: | 5077 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |