PAX3 Rabbit Polyclonal Antibody (CAB13930)
- SKU:
- CAB13930
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | PAX3 Rabbit Polyclonal Antibody |
SKU: | CAB13930 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 341-441 of human PAX3 (NP_852122.1). |
Sequence: | QSTI PSNP DSSS AYCL PSTR HGFS SYTD SFVP PSGP SNPM NPTI GNGL SPQV MGLL TNHG GVPH QPQT DYAL SPLT GGLE PTTT VSAS CSQR LDHM KSLD S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | WS1; WS3; CDHS; HUP2; PAX-3; PAX3 |
Positive Sample: | Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 53kDa |
Observed MW: | 53kDa |
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Purification Method: | Affinity purification |
Gene ID: | 5077 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |