The PASK Polyclonal Antibody (CAB8995) is a powerful tool for researchers studying the PASK protein, a key player in cellular metabolism and energy regulation. This antibody, raised in rabbits, is highly specific to human PASK and has been validated for use in Western blot applications. By binding to the PASK protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential tool for studies in metabolism, diabetes, and cancer research.
PASK, also known as PAS kinase, is a crucial regulator of cellular energy balance and glucose metabolism. Its role in coordinating metabolic pathways and responding to nutrient availability makes it a promising target for therapeutic interventions in metabolic disorders and cancer. By investigating the activity of PASK, researchers can gain valuable insights into the mechanisms underlying these diseases and develop targeted therapies to modulate PASK function for therapeutic benefit.
Product Name:
PASK Rabbit Polyclonal Antibody
SKU:
CAB8995
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1194-1323 of human PASK (NP_055963.2).
This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
23178
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PASK Rabbit pAb (CAB8995) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
