The PARVB Polyclonal Antibody (CAB13161) is a valuable tool for researchers studying PARVB, a protein involved in cell adhesion and migration processes. The antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for various applications such as Western blotting and immunohistochemistry.PARVB, also known as parvin beta, plays a crucial role in cell adhesion complexes and is implicated in cell signaling pathways related to cancer progression and metastasis.
By targeting PARVB with this antibody, researchers can explore its function in different cell types and tissues, advancing our understanding of its role in cancer biology and potential therapeutic targets.Overall, the PARVB Polyclonal Antibody is a reliable tool for investigating the functions and mechanisms of PARVB in cancer research and other related fields, providing valuable insights into potential diagnostic and therapeutic strategies.
Product Name:
PARVB Rabbit Polyclonal Antibody
SKU:
CAB13161
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human PARVB (NP_037459.2).
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29780
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PARVB Rabbit pAb (CAB13161) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
