The PARS2 Polyclonal Antibody (CAB16512) is a valuable tool for researchers studying PARS2, a protein involved in mitochondrial function and ribosome biogenesis. This antibody is produced in rabbits and has been validated for use in Western blot applications. It specifically binds to the PARS2 protein, allowing for accurate detection and analysis in a variety of cell types.PARS2 plays a critical role in maintaining mitochondrial function and protein synthesis, making it a key target for research in the fields of cell biology and metabolism. Dysregulation of PARS2 has been linked to various diseases, including metabolic disorders and mitochondrial dysfunction.
Understanding the function and regulation of PARS2 is essential for uncovering its potential role in disease pathology and developing targeted treatments.Overall, the PARS2 Polyclonal Antibody (CAB16512) is a reliable tool for researchers looking to delve into the molecular mechanisms of PARS2 and its implications in health and disease. Its specificity and sensitivity make it an ideal choice for various research applications in the fields of biochemistry, molecular biology, and beyond.
Product Name:
PARS2 Rabbit Polyclonal Antibody
SKU:
CAB16512
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-220 of human PARS2 (NP_689481.2).
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of proline to tRNA molecules. Mutations have been found in this gene in some patients with Alpers syndrome.
Purification Method:
Affinity purification
Gene ID:
25973
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PARS2 Rabbit pAb (CAB16512) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
