The PARP8 Polyclonal Antibody (CAB12894) is a valuable tool for researching PARP8, a member of the poly (ADP-ribose) polymerase (PARP) family of enzymes involved in DNA damage repair and genomic stability. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PARP8 protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it ideal for studies in molecular biology and cancer research.PARP8 is known for its role in DNA repair mechanisms, particularly in response to DNA damage caused by genotoxic stress. Dysregulation of PARP8 activity has been implicated in various diseases, including cancer, where impaired DNA repair can lead to genomic instability and tumor development.
Investigating the function of PARP8 is crucial for understanding its potential as a target for therapeutic intervention in cancer treatment and other related fields.Overall, the PARP8 Polyclonal Antibody offers researchers a reliable tool for studying the role of PARP8 in DNA repair processes and its implications for disease development. Its specificity and sensitivity make it a valuable asset for investigating the molecular mechanisms underlying genomic stability and potential therapeutic strategies targeting PARP8 function.
Product Name:
PARP8 Rabbit Polyclonal Antibody
SKU:
CAB12894
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PARP8 (NP_001171527.1).
Enables protein ADP-ribosylase activity. Involved in protein auto-ADP-ribosylation and protein mono-ADP-ribosylation.
Purification Method:
Affinity purification
Gene ID:
79668
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PARP8 Rabbit pAb (CAB12894) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
