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PARP2 Monoclonal Antibody [PAT29G4A] (CPAB0179)

SKU:
CPAB0179
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT29G4A
Applications:
WB
ELISA
$179
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Description

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PARP2 Monoclonal Antibody [PAT29G4A] (CPAB0179)

The PARP2 Polyclonal Antibody (CPAB0179) is a valuable tool for researchers studying the role of PARP2 in DNA repair and other cellular processes. This antibody, generated in rabbits, shows high specificity and sensitivity towards human PARP2 protein, making it ideal for use in Western blot and immunohistochemistry applications.PARP2, a member of the poly (ADP-ribose) polymerase family, is involved in DNA damage response and plays a crucial role in maintaining genomic stability. Dysregulation of PARP2 has been linked to various diseases, including cancer and neurodegenerative disorders, making it an attractive target for therapeutic interventions.

By using the PARP2 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of PARP2 in different cellular contexts, advancing our understanding of its role in health and disease. This antibody is a valuable tool for scientists studying DNA repair mechanisms, cancer biology, and potential therapeutic strategies targeting PARP2.

Product Name:PARP2 Antibody
Product Sku:CPAB0179
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PARP2 mAb, clone PAT29G4A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PARP2 protein 233-583 amino acids  purified from Ecoli.
Clone:PAT29G4A.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:PARP2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:Poly (ADP-Ribose) Polymerase 2 (PARP2) contains a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. PARP2 is capable of catalyzing a poly (ADP-ribosyl)ation reaction. The basic residues within the N-terminal area of this protein can bear potential DNA-binding properties, and can be engaged in the nuclear and/or nucleolar targeting of the protein. There has been found two alternatively spliced transcript variants encoding distinct isoforms.
Synonyms:ADPRT2, ADPRTL2, ADPRTL3, ARTD2, pADPRT-2, PARP-2, Poly [ADP-ribose] polymerase 2, hPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, NAD (+) ADP-ribosyltransferase 2, Poly [ADP-ribose] synthase 2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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