UniProt Protein Function: | PARP14: Enhances STAT6-dependent transcription. Has ADP-ribosyltransferase activity. 5 isoforms of the human protein are produced by alternative splicing.Protein type: EC 2.4.2.30; Transcription, coactivator/corepressor; TransferaseChromosomal Location of Human Ortholog: 3q21.1Cellular Component: cytoplasm; cytosol; membrane; nucleusMolecular Function: enzyme binding; NAD+ ADP-ribosyltransferase activity; protein binding; RNA bindingBiological Process: innate immune response; negative regulation of gene expression; negative regulation of tyrosine phosphorylation of STAT protein; positive regulation of interleukin-4-mediated signaling pathway; positive regulation of tyrosine phosphorylation of STAT protein; protein ADP-ribosylation; regulation of transcription, DNA-templated; transcription, DNA-dependent |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016] |
UniProt Code: | Q460N5 |
NCBI GenInfo Identifier: | 154813199 |
NCBI Gene ID: | 54625 |
NCBI Accession: | NP_060024.2 |
UniProt Secondary Accession: | Q460N5 |
UniProt Related Accession: | Q460N5 |
Molecular Weight: | |
NCBI Full Name: | protein mono-ADP-ribosyltransferase PARP14 |
NCBI Synonym Full Names: | poly(ADP-ribose) polymerase family member 14 |
NCBI Official Symbol: | PARP14Â Â |
NCBI Official Synonym Symbols: | BAL2; ARTD8; pART8; PARP-14Â Â |
NCBI Protein Information: | protein mono-ADP-ribosyltransferase PARP14; poly [ADP-ribose] polymerase 14 |
UniProt Protein Name: | Poly [ADP-ribose] polymerase 14 |
UniProt Synonym Protein Names: | ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2 |
Protein Family: | |
UniProt Gene Name: | PARP14Â Â |
UniProt Entry Name: | |