The PARP12 Polyclonal Antibody (CAB14317) is a valuable tool for researchers studying PARP12, a member of the poly(ADP-ribose) polymerase (PARP) family involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically targets the PARP12 protein, allowing for accurate detection and analysis in different cell types, making it ideal for studies in cell biology and cancer research.PARP12 is known for its role in regulating DNA repair, gene expression, and stress responses, making it a crucial protein in maintaining genome integrity and cellular homeostasis.
Dysregulation of PARP12 has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target. Research on PARP12 is essential for developing treatments that target specific pathways involved in disease progression and treatment resistance.Overall, the PARP12 Polyclonal Antibody is a valuable tool for researchers interested in studying the function and regulation of PARP12 in various cellular processes and disease states, offering insights that could lead to the development of novel therapeutic strategies.
Product Name:
PARP12 Rabbit Polyclonal Antibody
SKU:
CAB14317
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 462-701 of human PARP12 (NP_073587.1).
Enables protein ADP-ribosylase activity. Involved in protein auto-ADP-ribosylation and protein mono-ADP-ribosylation. Predicted to be located in nucleus.
Purification Method:
Affinity purification
Gene ID:
64761
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PARP12 Rabbit pAb (CAB14317) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
