The PARP11 Polyclonal Antibody (PACO11074) is specially designed for research involving PARP11, a member of the Poly(ADP-ribose) polymerase (PARP) family implicated in DNA repair processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PARP11 protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent tool for studies in the fields of DNA repair, genomics, and cancer research.
PARP11 is involved in DNA damage repair mechanisms, making it a key player in maintaining genomic stability and integrity. Dysregulation of PARP11 function has been associated with increased susceptibility to genotoxic stress and may contribute to the development of cancer and other genetic diseases. Investigating the role and activity of PARP11 is essential for advancing our understanding of DNA repair processes and developing targeted therapies for diseases linked to genomic instability.