PARL Rabbit Polyclonal Antibody (CAB8232)
- SKU:
- CAB8232
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PARL Rabbit Polyclonal Antibody |
SKU: | CAB8232 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human PARL (NP_001032728.1). |
Sequence: | MAWR GWAQ RGWG CGQA WGAS VGGR SCEE LTAV LTPP QLLG RRFN FFIQ QKCG FRKA PRKV EPRR SDPG TSGE AYKR SALI PPVE ETVF YPSP YPIR SLIK PLFF TVGF TGCA FGSA AIWQ YESL KSRV QSYF DGIK ADWL DSIR PQKE GDFR KEIN KWWN NLSD GQRT VT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PSARL; PSARL1; RHBDS1; PRO2207; PSENIP2; PARL |
Positive Sample: | HepG2,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane, Multi-pass membrane protein, Nucleus. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.
Purification Method: | Affinity purification |
Gene ID: | 55486 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |