The Park7 Rabbit Monoclonal Antibody (CAB19097) is a cutting-edge tool designed for researchers studying the Park7 protein, also known as DJ-1. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it an invaluable asset for studies in Parkinson's disease, cancer, and other conditions where Park7 is implicated.Park7, a multifunctional protein involved in oxidative stress response and cell survival pathways, has been linked to neurodegenerative disorders like Parkinson's disease. The Park7 Rabbit Monoclonal Antibody binds specifically to the Park7 protein, enabling precise detection and analysis in various experimental settings, including Western blot applications.
Research into the role of Park7 in cellular processes and disease pathology is crucial for developing targeted therapies and understanding disease mechanisms. The Park7 Rabbit Monoclonal Antibody provides researchers with a powerful tool to delve into the functions and pathways involving Park7, paving the way for advancements in neurology, oncology, and beyond.
Product Name:
PARK7 Rabbit Monoclonal Antibody
SKU:
CAB19097
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DJ-1/PARK7 (Q99497).
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
11315
Clone Number:
ARC0354
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DJ-1/PARK7 antibody (CAB19097) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
