PARK7 P1E12AT Monoclonal Antibody [P1E12AT] (CPAB0602)
- SKU:
- CPAB0602
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
Description
PARK7 P1E12AT Monoclonal Antibody [P1E12AT] (CPAB0602)
The PARK7 (P1E12AT) Antibody (CPAB0602) is a valuable tool for researchers studying the PARK7 protein, also known as DJ-1, which plays a crucial role in oxidative stress response and neuroprotection. This polyclonal antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.PARK7 is a multifunctional protein that has been implicated in various cellular processes, including cell survival, mitochondrial function, and regulation of gene expression. Its dysregulation has been associated with neurodegenerative disorders such as Parkinson's disease, making it a promising target for therapeutic intervention.
By binding to the PARK7 protein, this antibody enables accurate detection and analysis of PARK7 expression in different cell types, providing valuable insights for researchers in neuroscience, neurology, and neurodegenerative disease research. Investigating the role of PARK7 in oxidative stress and neuroprotection could lead to the development of novel treatment strategies for neurological disorders.
Product Name: | PARK7 P1E12AT Antibody |
Product Sku: | CPAB0602 |
Size: | 5μg |
Host Species: | Mouse IgG2b |
Immunogen: | Anti-human PARK7 mAb, clone P1E12AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PARK7 protein 1-189 amino acids purified from Ecoli. |
Clone: | P1E12AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | PARK7 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | The PARK7 is a ubiquitously expressed protein involved in various cellular processes including spermatogenesis and fertilization, cancer, RNA-binding, androgen-receptor signaling and oxidative stress. Mutations in the PARK7 are the cause of autosomal recessive early-onset Parkinson's disease 7 (Park7). |
Synonyms: | PARK7, Parkinson disease protein 7, Oncogene DJ-1, Parkinson disease (autosomal recessive, early onset) 7. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |