Parkin Rabbit Polyclonal Antibody (CAB0968)
- SKU:
- CAB0968
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | Parkin Rabbit Polyclonal Antibody |
SKU: | CAB0968 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 81-280 of human Parkin (NP_004553.2). |
Sequence: | NATG GDDP RNAA GGCE REPQ SLTR VDLS SSVL PGDS VGLA VILH TDSR KDSP PAGS PAGR SIYN SFYV YCKG PCQR VQPG KLRV QCST CRQA TLTL TQGP SCWD DVLI PNRM SGEC QSPH CPGT SAEF FFKC GAHP TSDK ETSV ALHL IATN SRNI TCIT CTDV RSPV LVFQ CNSR HVIC LDCF HLYC VTRL NDRQ FVHD |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PDJ; AR-JP; LPRS2; PARK2; Parkin |
Positive Sample: | 293F transfected with Parkin |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum, Mitochondrion, Nucleus, cytosol. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
Purification Method: | Affinity purification |
Gene ID: | 5071 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |