The PARP Monoclonal Antibody is a vital tool for researchers studying PARP, a key enzyme involved in DNA repair and programmed cell death processes. This antibody, produced through monoclonal techniques, exhibits high specificity for PARP and has been rigorously tested for use in Western blot applications. It effectively binds to the PARP protein, enabling precise detection and analysis in a variety of cell types.PARP, also known as poly (ADP-ribose) polymerase, is essential for maintaining genomic stability and cell survival in response to DNA damage.
Dysregulation of PARP activity has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions. Investigating the function of PARP with this antibody is crucial for advancing our understanding of these diseases and developing targeted therapies for improved patient outcomes.
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8505
Clone Number:
ARC59258
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat testis using PARG Rabbit mAb (CAB23276) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
