PARD6A Rabbit Polyclonal Antibody (CAB3064)
- SKU:
- CAB3064
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | PARD6A Rabbit Polyclonal Antibody |
SKU: | CAB3064 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PARD6A (Q9NPB6). |
Sequence: | MARP QRTP ARSP DSIV EVKS KFDA EFRR FALP RASV SGFQ EFSR LLRA VHQI PGLD VLLG YTDA HGDL LPLT NDDS LHRA LASG PPPL RLLV QKRA EADS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PAR6; PAR6C; TAX40; PAR-6A; TIP-40; PAR6alpha; PARD6A |
Positive Sample: | SW620,HT-29,Jurkat,U-251MG,Raji,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasm, ruffle, tight junction. |
Calculated MW: | 37kDa |
Observed MW: | 47kDa |
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 50855 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |