The Parathyroid Hormone Polyclonal Antibody (CAB5846) is a vital tool for researchers studying parathyroid hormone, a key regulator of calcium and phosphate metabolism in the body. This antibody, produced in rabbits, is highly specific for human parathyroid hormone and has been validated for use in various applications such as Western blotting.Parathyroid hormone plays a crucial role in maintaining calcium levels in the blood and bone, making it a critical hormone for overall bone health and mineral balance. Dysregulation of parathyroid hormone can lead to disorders such as hyperparathyroidism or hypoparathyroidism, which can have serious implications for bone health and overall well-being.
The Parathyroid Hormone Polyclonal Antibody (CAB5846) enables researchers to detect and analyze parathyroid hormone levels in various cell types, providing valuable insights into its role in health and disease. This antibody is a valuable tool for studies in endocrinology, bone metabolism, and related fields, ultimately contributing to a better understanding of parathyroid hormone function and potential therapeutic interventions.
Recombinant fusion protein containing a sequence corresponding to amino acids 20-115 of human Parathyroid Hormone (Parathyroid Hormone (PTH)) (NP_000306.1).
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5741
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Parathyroid Hormone (Parathyroid Hormone (PTH)) antibody (CAB5846) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
