SPG7 Rabbit Polyclonal Antibody (CAB10249)
- SKU:
- CAB10249
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SPG7 Rabbit Polyclonal Antibody |
SKU: | CAB10249 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SPG7 (NP_003110.1). |
Sequence: | MAVL LLLL RALR RGPG PGPR PLWG PGPA WSPG FPAR PGRG RPYM ASRP PGDL AEAG GRAL QSLQ LRLL TPTF EGIN GLLL KQHL VQNP VRLW QLLG GTFY FNTS RLKQ KNKE KDKS KGKA PEED EEER RRRE RDDQ MYRE RLRT LLVI AVVM SLLN ALST SGGS ISWN DFVH EMLA KGEV QRVQ VVPE SDVV EVYL HPGA VVFG RPRL ALMY RMQV ANID KFEE KLRA AEDE LNIE AKDR IPVS YKRT GF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CAR; PGN; CMAR; SPG5C; SPG7 |
Positive Sample: | U-87 MG,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane, Multi-pass membrane protein. |
Calculated MW: | 88kDa |
Observed MW: | 88kDa |
This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 6687 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |