The PAR2 Rabbit Monoclonal Antibody (CAB5103) is a cutting-edge tool for researchers studying Protease-Activated Receptor 2 (PAR2), a key protein involved in inflammatory responses and pain perception. This antibody, developed using rabbit monoclonal technology, offers high specificity and sensitivity when detecting PAR2 in human samples, making it an essential resource for Western blot applications.PAR2 is known for its role in mediating inflammation and pain signaling, making it a promising target for therapeutic intervention in conditions such as inflammatory bowel disease, arthritis, and neuropathic pain.
By using the PAR2 Rabbit Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of PAR2 in different cell types, advancing our understanding of its role in health and disease.With its superior performance and reliability, the PAR2 Rabbit Monoclonal Antibody (CAB5103) is a valuable tool for immunology and pain research, offering researchers the opportunity to explore new avenues for therapeutic development and personalized medicine.
Product Name:
PAR2 Rabbit Monoclonal Antibody
SKU:
CAB5103
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 298-397 of human PAR2 (P55085).
HCT 116,Hep G2,BxPC-3,Mouse large intestine,Rat large intestine
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Multi-pass membrane protein.
Calculated MW:
44kDa
Observed MW:
55kDa
This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity.
Purification Method:
Affinity purification
Gene ID:
2150
Clone Number:
ARC1246
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PAR2 Rabbit mAb (CAB5103) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
