The Papillary Renal Cell Carcinoma Polyclonal Antibody offered by Assay Genie (SKU: AG20001) is designed for researchers studying papillary renal cell carcinoma, a type of kidney cancer that accounts for about 15-20% of all renal cell carcinomas. This antibody, raised in rabbits, is highly specific to human papillary renal cell carcinoma samples and has been validated for use in various applications, including immunohistochemistry and Western blot.The antibody targets specific proteins associated with papillary renal cell carcinoma, allowing for accurate detection and analysis in tumor samples.
It is an invaluable tool for studying the molecular mechanisms underlying this type of cancer and for identifying potential therapeutic targets. Researchers can use this antibody to better understand the pathogenesis of papillary renal cell carcinoma and to develop more effective diagnostic and treatment strategies.Overall, the Papillary Renal Cell Carcinoma Polyclonal Antibody from Assay Genie is a valuable resource for researchers seeking to advance our knowledge of this specific type of kidney cancer and ultimately improve patient outcomes.
A synthetic peptide of Human Papillary renal cell carcinoma.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
TPRC; RCCP1; Papillary renal cell carcinoma
Positive Sample:
HeLa
Conjugate:
Unconjugated
Cellular Localization:
nuclear speck, nucleoplasm, nucleus
Calculated MW:
52kDa
Observed MW:
66kDa
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.
Purification Method:
Affinity purification
Gene ID:
5546
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of HeLa, using Papillary renal cell carcinoma antibody (CAB18781) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
