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PAOX Antibody (PACO11067)

SKU:
PACO11067
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
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Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:PAOX Antibody (PACO11067)
Antibody SKU:PACO11067
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human PAOX
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:polyamine oxidase (exo-N4-amino);PAOX;DKFZp434J245;MGC45464;PAO ;
UniProt Protein Function:PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 1.5.3.13; Oxidoreductase

Chromosomal Location of Human Ortholog: 10q26.3

Cellular Component: peroxisomal matrix

Molecular Function:polyamine oxidase activity; receptor binding

Biological Process: spermine catabolic process; xenobiotic metabolic process; polyamine biosynthetic process; putrescine biosynthetic process; polyamine catabolic process; spermidine catabolic process; putrescine catabolic process; polyamine metabolic process

UniProt Code:Q6QHF9
NCBI GenInfo Identifier:51316248
NCBI Gene ID:196743
NCBI Accession:Q6QHF9.3
UniProt Secondary Accession:Q6QHF9,Q5VWY0, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0 Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, D3DXI6,
UniProt Related Accession:Q6QHF9
Molecular Weight:649
NCBI Full Name:Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
NCBI Synonym Full Names:polyamine oxidase (exo-N4-amino)
NCBI Official Symbol:PAOX  
NCBI Official Synonym Symbols:PAO  
NCBI Protein Information:peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase
UniProt Protein Name:Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Synonym Protein Names:Polyamine oxidase
Protein Family:Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Gene Name:PAOX  
UniProt Entry Name:PAOX_HUMAN

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