The PANX1 Polyclonal Antibody (CAB13587) is a valuable tool for researchers studying PANX1, a protein that forms channels in cell membranes and plays a crucial role in various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.PANX1 is involved in cell communication, inflammation, and immune response regulation, making it a key target for investigation in fields such as immunology and cancer research. The PANX1 Polyclonal Antibody binds specifically to PANX1, allowing for the detection and analysis of this important protein in a variety of cell types.
By understanding the function and regulation of PANX1, researchers can gain insights into its implications in diseases such as cancer, autoimmune disorders, and inflammatory conditions. This antibody provides a reliable tool for exploring the role of PANX1 in physiological and pathological processes, ultimately contributing to the development of potential therapeutic strategies targeting PANX1.
Product Name:
Pannexin 1 Rabbit Polyclonal Antibody
SKU:
CAB13587
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 297-426 of human Pannexin 1 (NP_056183.2).
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
Purification Method:
Affinity purification
Gene ID:
24145
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Pannexin 1 antibody (CAB13587) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
