The Pannexin-1 Rabbit Monoclonal Antibody (CAB5167) is a specialized antibody designed for research involving Pannexin-1, a channel protein involved in various cellular processes, including cell signaling and communication. This high-quality antibody, generated in rabbits, has been rigorously validated for use in Western blot applications and is highly reactive with human samples.Pannexin-1 is known to be involved in diverse physiological and pathological conditions, making it a crucial target for studies in fields such as neuroscience, immunology, and cancer research. By targeting the Pannexin-1 protein, this antibody enables accurate detection and analysis of Pannexin-1 expression in different cell types, providing researchers with a valuable tool for investigating its role in various biological processes.
With its ability to specifically bind to Pannexin-1, this antibody is essential for gaining insights into the function of this channel protein and its potential implications in disease mechanisms. Researchers interested in uncovering the molecular mechanisms and signaling pathways involving Pannexin-1 will find this antibody indispensable for advancing their understanding of cellular communication and physiological regulation.
Product Name:
Pannexin 1 Rabbit Monoclonal Antibody
SKU:
CAB5167
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 327-426 of human Pannexin 1 (Q96RD7).
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
Purification Method:
Affinity purification
Gene ID:
24145
Clone Number:
ARC1207
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Pannexin 1 Rabbit mAb (CAB5167) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
