null

pan-Trk Monoclonal Antibody

SKU:
CAB23241
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

pan-Trk Monoclonal Antibody (CAB23241)

The Pan-TRK Monoclonal Antibody is a cutting-edge tool for researchers studying TRK proteins, a family of receptors involved in cellular growth, differentiation, and survival. This antibody, produced through monoclonal antibody technology, exhibits high specificity and sensitivity for detecting TRK proteins in a variety of biological samples.TRK proteins, including TRKA, TRKB, and TRKC, play crucial roles in neuronal development and function, as well as in various cancers where they can be overexpressed or mutated. The Pan-TRK Monoclonal Antibody allows for precise detection and analysis of these proteins in Western blot applications, making it an essential tool for researchers investigating the role of TRK proteins in cancer biology and neurobiology.

By targeting TRK proteins, researchers can gain valuable insights into the mechanisms underlying cancer growth and progression, as well as potential therapeutic targets for personalized medicine approaches. The Pan-TRK Monoclonal Antibody is a reliable and versatile tool for advancing research in oncology and neuroscience, contributing to the development of novel diagnostic and therapeutic strategies for TRK-related diseases.

Product Name:pan-Trk Monoclonal Antibody
Product Code:CAB23241
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC59539
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:SH-SY5Y, Mouse brain, Rat brain
Cellular Location:axon, dendrite, early endosome, late endosome, plasma membrane

Neurotrophic tyrosine kinase (NTRK) is a family of receptor tyrosine kinase.The NTRK gene family contains three members, NTRK1, NTRK2 and NTRK3, which produce TRKA, TRKB and TRKC proteins, respectively.TRK kinases leads to cell differentiation and may play important roles in normal neural functions.Rearrangements in the NTRK genes can result in two genes fusing together and producing altered TRK proteins, which can lead to uncontrolled growth of cancer cells. Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are an actionable biomarker for cancer therapy and can be found in over 25 different types of cancer.

Immunogen:A synthesized peptide derived from human pan-Trk.
Sequence:Email for sequence
Observed MW:120-140kDa

Related Products