Pan Phospho-Tyrosine Rabbit Polyclonal Antibody (CABP0905)
The Pan-Phospho-Tyrosine Rabbit Polyclonal Antibody (CABP0905) is a valuable tool for studying protein phosphorylation events in cells. This antibody recognizes a wide range of proteins containing phosphorylated tyrosine residues, allowing for the detection and analysis of signaling pathways involved in various cellular processes.Phosphorylation events on tyrosine residues are crucial for the regulation of cell growth, differentiation, and survival. Abnormalities in tyrosine phosphorylation have been linked to diseases such as cancer, diabetes, and neurological disorders. The Pan-Phospho-Tyrosine Antibody enables researchers to investigate the role of tyrosine phosphorylation in these diseases and identify potential therapeutic targets.
This highly specific antibody, validated for use in Western blot applications, is raised in rabbits and shows strong reactivity with human samples. Its versatility in detecting a broad range of phospho-tyrosine proteins makes it an excellent choice for studies in cell signaling, cancer biology, and drug development. Don't miss out on the opportunity to enhance your research with the Pan-Phospho-Tyrosine Rabbit Polyclonal Antibody (CABP0905).
Product Name:
Pan Phospho-Tyrosine Rabbit Polyclonal Antibody
SKU:
CABP0905
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat,Other (Wide Range Predicted)
Immunogen:
A synthetic peptide corresponding to a sequence containing phosphorylated S & T.
Tested Applications:
WBIF/ICCELISA
Recommended Dilution:
WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Positive Sample:
Jurkat
Observed MW:
20-70kDa
Tyrosine phosphorylation (pTyr), much of which occurred on localized multiple sites, initiates cellular signaling, governs cellular functions, and its dysregulation is implicated in many diseases, especially cancers. pTyr-specific sensing is of great significance for understanding disease states and developing targeted anticancer drugs.
Purification Method:
Affinity purification
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using Pan Phospho-Tyrosine pAb (CABP0905) at 1:1000 dilution.Jurkat cells were treated by Pervanadate (1 mM) at 37℃ for 30 minutes.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
