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pan 14-3-3 Polyclonal Antibody

SKU:
CAB23674
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
NHP - Monkey
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

pan 14-3-3 Polyclonal Antibody (CAB23674)

The Pan 14-3-3 Polyclonal Antibody is specifically designed for research involving the 14-3-3 protein family, which plays essential roles in signal transduction, cell cycle regulation, and apoptosis. The antibody, produced in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blotting and immunohistochemistry.The 14-3-3 proteins are highly conserved and interact with a wide range of target proteins, influencing different cellular processes. This antibody binds to the 14-3-3 protein, facilitating its detection and analysis in diverse cell types.

Its versatility makes it ideal for studies in cell biology, neuroscience, and cancer research.Understanding the functions and interactions of the 14-3-3 protein family is crucial for unraveling the complexities of cellular signaling pathways and identifying potential therapeutic targets for various diseases. The Pan 14-3-3 Polyclonal Antibody is a valuable tool for researchers seeking to delve deeper into the roles of 14-3-3 proteins in health and disease.

Product Name:pan 14-3-3 Polyclonal Antibody
Product Code:CAB23674
Reactivity:Human, Mouse, Rat, African green monkey
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat, African green monkey
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:HeLa, K-562, Jurkat, H-4-11-E, COS7, NIH/3T3

This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Immunogen:Recombinant protein of human pan 14-3-3.
Sequence:Email for sequence
Synonyms:YWHA, S1C5, HS1, 14-3-3
Calculated MW:27kDa/28kDa
Observed MW:27-29kDa

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