The PALLD Polyclonal Antibody (CAB12362) is a valuable tool for researchers studying the PALLD protein, which plays a crucial role in cell division and DNA damage response. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the PALLD protein, this antibody enables the detection and analysis of PALLD in various cell types, making it an ideal choice for studies in cell biology and cancer research.
PALLD, also known as Phosphorylated Adenomatous Polyposis Coli-Linked Partner of Disc Large, is involved in maintaining genomic stability and regulating cell proliferation. Its activity in these processes makes it a target of interest for researchers investigating cancer development and progression. Understanding the role of PALLD can provide valuable insights into the mechanisms of tumorigenesis and identify potential therapeutic targets for cancer treatment.
Product Name:
PALLD Rabbit Polyclonal Antibody
SKU:
CAB12362
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 383-672 of human PALLD (NP_001159582.1).
This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23022
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PALLD Rabbit pAb (CAB12362) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
