PAK6 Rabbit Polyclonal Antibody (CAB7821)
- SKU:
- CAB7821
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PAK6 Rabbit Polyclonal Antibody |
SKU: | CAB7821 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PAK6 (NP_064553.1). |
Sequence: | MFRK KKKK RPEI SAPQ NFQH RVHT SFDP KEGK FVGL PPQW QNIL DTLR RPKP VVDP SRIT RVQL QPMK TVVR GSAM PVDG YISG LLND IQKL SVIS SNTL RGRS PTSR RRAQ SLGL LGDE HWAT DPDM YLQS PQSE RTDP HGLY LSCN GGTP AGHK QMPW PEPQ SPRV LPNG LAAK AQSL GPAE FQGA SQRC LQLG ACLQ SSPP GASP PTGT NRHG MKAA KHGS EEAR PQSC LVGS ATGR PGGE GSPS PKTR ESSL KRRL FRSM FLST AA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PAK5; PAK6 |
Positive Sample: | BxPC-3,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 75kDa |
Observed MW: | 75kDa |
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 56924 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |