PAK5 Rabbit Polyclonal Antibody (CAB15872)
- SKU:
- CAB15872
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
Product Name: | PAK5 Rabbit Polyclonal Antibody |
SKU: | CAB15872 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human PAK5 (NP_065074.1). |
Sequence: | RKSL VGTP YWMA PEVI SRLP YGTE VDIW SLGI MVIE MIDG EPPY FNEP PLQA MRRI RDSL PPRV KDLH KVSS VLRG FLDL MLVR EPSQ RATA QELL GHPF L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PAK7; PAK5 |
Positive Sample: | U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Nucleus. |
Calculated MW: | 81kDa |
Observed MW: | 81kDa |
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
Purification Method: | Affinity purification |
Gene ID: | 57144 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |