PAK3 Rabbit Polyclonal Antibody (CAB16942)
- SKU:
- CAB16942
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PAK3 Rabbit Polyclonal Antibody |
SKU: | CAB16942 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAK3 (NP_001121638.1). |
Sequence: | MSDG LDNE EKPP APPL RMNS NNRD SSAL NHSS KPLP MAPE EKNK KARL RSIF PGGG DKTN KKKE KERP EISL PSDF EHTI HVGF DAVT GEFT GIPE QWAR |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | ARA; bPAK; MRX30; MRX47; OPHN3; PAK-3; XLID30; PAK3beta; beta-PAK; PAK3 |
Positive Sample: | U-251MG,Rat brain,Rat testis |
Cellular Localization: | cytoplasm, cytosol, endosome, glutamatergic synapse, plasma membrane, postsynaptic density |
Calculated MW: | 62kDa |
Observed MW: | 80kDa |
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 5063 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |