The Pak2 Polyclonal Antibody is a valuable tool for researchers studying Pak2, a key protein kinase involved in cell signaling pathways related to cell proliferation, survival, and migration. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting Pak2 in human samples, making it suitable for Western blot experiments.Pak2, a member of the p21-activated kinase (Pak) family, is known to play a pivotal role in various cellular processes, including cytoskeletal dynamics, cell motility, and cell adhesion.
Dysregulation of Pak2 has been implicated in cancer progression, making it an attractive target for therapeutic intervention.By using the Pak2 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of Pak2 in different cell types and disease contexts. This antibody is an essential tool for studies focusing on understanding Pak2's role in cancer biology, cell signaling, and other pathological conditions. Explore the potential of Pak2 with the Pak2 Polyclonal Antibody for your research needs.
Product Name:
PAK2 Polyclonal Antibody
SKU:
CAB21522
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PAK2 (NP_002568.2).
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Purification Method:
Affinity purification
Gene ID:
5062
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts from wild type(WT) and PAK2 knockout (KO) HeLa(KO) cells, using PAK2 antibody (CAB21522) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
