PAK2 Polyclonal Antibody (CAB21522)
- SKU:
- CAB21522
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | PAK2 Polyclonal Antibody |
SKU: | CAB21522 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PAK2 (NP_002568.2). |
Sequence: | MSDN GELE DKPP APPV RMSS TIFS TGGK DPLS ANHS LKPL PSVP EEKK PRHK IISI FSGT EKGS KKKE KERP EISP PSDF EHTI HVGF DAVT GEFT GMPE QWAR LLQT SNIT KLEQ KKNP QAVL DVLK FYDS NTVK QKYL SFTP PEKD GFPS GTPA LNAK GTEA PAVV TEEE DDDE ETAP PVIA PRPD HTKS IYTR SVID PVPA PVGD SHVD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | KNO2; PAK65; PAKgamma; K2 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasm, Lipid-anchor, Membrane, Nucleus, perinuclear region. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Purification Method: | Affinity purification |
Gene ID: | 5062 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |