PAK2 Rabbit Polyclonal Antibody (CAB7333)
- SKU:
- CAB7333
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | PAK2 Rabbit Polyclonal Antibody |
SKU: | CAB7333 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-240 of human PAK2 (NP_002568.2). |
Sequence: | PQAV LDVL KFYD SNTV KQKY LSFT PPEK DGFP SGTP ALNA KGTE APAV VTEE EDDD EETA PPVI APRP DHTK SIYT RSVI DPVP APVG DSHV DGAA KSLD KQKK KTKM TDEE IMEK LRTI V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | KNO2; PAK65; PAKgamma; PAK2 |
Positive Sample: | HeLa,SKOV3,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasm, Lipid-anchor, Membrane, Nucleus, perinuclear region. |
Calculated MW: | 58kDa |
Observed MW: | 60kDa |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Purification Method: | Affinity purification |
Gene ID: | 5062 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |