PAI-1/Serpin E1 Rabbit Monoclonal Antibody (CAB19096)
- SKU:
- CAB19096
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
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Description
Product Name: | PAI-1/Serpin E1 Rabbit Monoclonal Antibody |
SKU: | CAB19096 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PAI-1/Serpin E1 (P05121). |
Sequence: | SKDR NVVF SPYG VASV LAML QLTT GGET QQQI QAAM GFKI DDKG MAPA LRHL YKEL MGPW NKDE ISTT DAIF VQRD LKLV QGFM PHFF RLFR STVK QVDF S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PAI; PAI1; PAI-1; PLANH1; PAI-1/Serpin E1 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 45kDa |
Observed MW: | 45kDa |
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.
Purification Method: | Affinity purification |
Gene ID: | 5054 |
Clone Number: | ARC0473 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |