The PACO16830 Polyclonal Antibody is a valuable tool for researchers studying CD300A, a cell surface molecule known for its role in immune regulation. This antibody, which has been raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CD300A protein, this antibody enables the detection and analysis of CD300A in various cell types, making it an ideal choice for studies in immunology and cancer research.CD300A, also referred to as an immune inhibitory receptor, plays a crucial role in immune homeostasis by regulating inflammation and suppressing allergic reactions.
Its importance in modulating immune responses makes it a promising target for research on conditions such as cancer, autoimmune disorders, and chronic inflammatory diseases. By understanding the activity of CD300A, researchers can work towards developing therapies that effectively modulate immune function in these disease contexts.
Antibody Name:
PAGE2 Antibody (PACO16830)
Antibody SKU:
PACO16830
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Fusion protein of human PAGE2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16830(PAGE2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16830(PAGE2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
PAGE-2 (prostate-associated gene 2 protein), also known as P antigen family member 2B, GAGEC2, CT16.4 or GAGEE2, is a 111 amino acid, protein that is expressed primarily in testis and belongs to the GAGE family. PAGE-2B (prostate-associated gene 2B protein), also designated putative G antigen family E member 3, P antigen family member 2B, CT16.5 or GAGEE3, also consists of 111 amino acid, and is a member of the GAGE family. Both proteins are encoded by genes that map to human chromosome X, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome lead to normal male development while two copies of X lead to normal female development.
Synonyms:
P antigen family, member 2 (prostate associated)
UniProt Protein Function:
PAGE2: Belongs to the GAGE family.Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xp11.21
