The PAG1 Polyclonal Antibody (CAB16303) is a valuable tool for researchers studying the PAG1 protein, a key player in signal transduction pathways involved in cell growth and differentiation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications.PAG1, also known as Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains, is a scaffolding protein that regulates intracellular signaling cascades by interacting with various kinases and adaptor proteins.
By targeting PAG1 with this antibody, researchers can gain insights into its role in cellular processes such as proliferation, migration, and survival.This antibody is essential for studies in cancer research, as aberrant expression of PAG1 has been implicated in tumorigenesis and metastasis. Furthermore, understanding the signaling pathways involving PAG1 can provide valuable information for the development of targeted therapies against cancer and other diseases associated with dysregulated cell growth.
Product Name:
Peroxiredoxin 1 (PAG) Rabbit Polyclonal Antibody
SKU:
CAB16303
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Peroxiredoxin 1 (PAG) (NP_060910.3).
The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation.
Purification Method:
Affinity purification
Gene ID:
55824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Peroxiredoxin 1 (PAG) Rabbit pAb (CAB16303) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
