The PADI4 Polyclonal Antibody (CAB16188) is specifically designed for research involving PADI4, a protein known for its role in immune regulation and the inflammatory response. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the PADI4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology and inflammatory diseases.PADI4, also known as peptidylarginine deiminase 4, is a key enzyme involved in the citrullination process, which plays a critical role in autoimmune diseases such as rheumatoid arthritis.
Understanding the functions and regulations of PADI4 is essential for developing targeted therapies and biomarkers for these conditions. Research utilizing the PADI4 Polyclonal Antibody can provide valuable insights into the mechanisms of autoimmune diseases and inflammation, ultimately leading to the development of more effective treatments.
Product Name:
PADI4 Rabbit Polyclonal Antibody
SKU:
CAB16188
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-663 of human PADI4 (NP_036519.2).
This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.
Purification Method:
Affinity purification
Gene ID:
23569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using PADI4 Rabbit pAb (CAB16188) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
