PADI2 Rabbit Polyclonal Antibody (CAB11711)
- SKU:
- CAB11711
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PADI2 Rabbit Polyclonal Antibody |
SKU: | CAB11711 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-210 of human PADI2 (NP_031391.2). |
Sequence: | WTDV YSAA PAGA QTFS LKHS EHVW VEVV RDGE AEEV ATNG KQRW LLSP STTL RVTM SQAS TEAS SDKV TVNY YDEE GSIP IDQA GLFL TAIE ISLD VDAD RDGV VEKN NPKK ASWT WGPE GQGA ILLV NCDR ETPW LPKE DCRD EKVY SKED LKDM SQMI LRTK GPDR LPAG YEIV LYIS MSDS D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PAD2; PDI2; PAD-H19; PADI2 |
Positive Sample: | mouse spleen,rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 76kDa |
Observed MW: | 75kDa |
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
Purification Method: | Affinity purification |
Gene ID: | 11240 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |