The PACSIN1 Polyclonal Antibody (CAB15827) is an essential tool for researchers studying PACSIN1, a protein involved in cellular processes such as endocytosis, membrane trafficking, and cytoskeleton organization. This antibody, produced in rabbits, specifically binds to PACSIN1 in human samples and is validated for use in Western blot applications. Its high reactivity allows for accurate detection and analysis of PACSIN1 in various cell types, making it ideal for investigations in cell biology and neuroscience research.PACSIN1, also known as protein kinase C and casein kinase substrate in neurons protein 1, plays a crucial role in the regulation of synaptic vesicle endocytosis, neuronal development, and neurotransmitter release.
Dysregulation of PACSIN1 has been implicated in neurological disorders such as Alzheimer's disease and Parkinson's disease, making it a promising target for therapeutic interventions. Understanding the function of PACSIN1 is essential for unraveling its role in neurobiology and developing novel treatments for neurological conditions.
Product Name:
PACSIN1 Rabbit Polyclonal Antibody
SKU:
CAB15827
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-390 of human PACSIN1 (NP_065855.1).
Enables phospholipid binding activity. Involved in plasma membrane tubulation. Located in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
29993
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using PACSIN1 Rabbit pAb (CAB15827) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
