PACS1 Rabbit Polyclonal Antibody (CAB12659)
- SKU:
- CAB12659
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | PACS1 Rabbit Polyclonal Antibody |
SKU: | CAB12659 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-560 of human PACS1 (NP_060496.2). |
Sequence: | SKGS LGKD TTSP MELA ALEK IKST WIKN QDDS LTET DTLE ITDQ DMFG DAST SLVV PEKV KTPM KSSK TDLQ GSAS PSKV EGVH TPRQ KRST PLKE RQLS KPLS ERTN SSDS ERSP DLGH STQI PRKV VYDQ LNQI LVSD A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 |
Synonyms: | SHMS; MRD17; PACS1 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus, trans-Golgi network. |
Calculated MW: | 105kDa |
Observed MW: | 105kDa |
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Purification Method: | Affinity purification |
Gene ID: | 55690 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |