PACRG Rabbit Polyclonal Antibody (CAB15956)
- SKU:
- CAB15956
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PACRG Rabbit Polyclonal Antibody |
SKU: | CAB15956 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human PACRG (NP_001073847.1). |
Sequence: | IIPI KNAL NLRN RQVI CVTL KVLQ HLVV SAEM VGKA LVPY YRQI LPVL NIFK NMNV NSGD GIDY SQQK RENI GDLI QETL EAFE RYGG ENAF INIK YVVP T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GLUP; PACRG2.1; PARK2CRG; HAK005771; PACRG |
Positive Sample: | 293T,A-549,BxPC-3,Raji,Mouse testis,Mouse lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, neuron projection, nucleus |
Calculated MW: | 33kDa |
Observed MW: | 35kDa |
This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 135138 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |