pAbPC1 Rabbit Polyclonal Antibody (CAB14872)
- SKU:
- CAB14872
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | pAbPC1 Rabbit Polyclonal Antibody |
SKU: | CAB14872 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PABPC1 (NP_002559.2). |
Sequence: | VTEM NGRI VATK PLYV ALAQ RKEE RQAH LTNQ YMQR MASV RAVP NPVI NPYQ PAPP SGYF MAAI PQTQ NRAA YYPP SQIA QLRP SPRW TAQG ARPH PFQN M |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:200 |
Synonyms: | PAB1; PABP; PABP1; PABPC2; PABPL1; pAbPC1 |
Positive Sample: | NIH/3T3,PC-12 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 71kDa |
Observed MW: | 75kDa |
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
Purification Method: | Affinity purification |
Gene ID: | 26986 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |