The P90RSK Polyclonal Antibody (CAB15718) is a valuable tool for researchers studying the p90 ribosomal S6 kinase (p90RSK) protein, which plays a key role in cell proliferation, differentiation, and survival. This antibody, produced in rabbits, demonstrates high specificity for human samples and is suitable for use in Western blot applications.p90RSK is a serine/threonine kinase that is activated by various growth factors and cellular stress signals. Its involvement in signaling pathways related to cell growth and survival makes it an important target for research in cancer biology and developmental biology. By detecting and analyzing the p90RSK protein in different cell types, this antibody can provide valuable insights into the mechanisms underlying cell signaling and growth regulation.
The potential implications of studying p90RSK extend to the field of drug development, as targeting this kinase may offer new therapeutic strategies for treating diseases such as cancer, where aberrant cell growth and survival signaling pathways play a significant role. Researchers interested in understanding the molecular mechanisms driving cell proliferation and survival processes will find the P90RSK Polyclonal Antibody to be a valuable resource for their investigations.
Product Name:
p90Rsk/RSK1/RPS6KA1 Rabbit Polyclonal Antibody
SKU:
CAB15718
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of human p90Rsk/RSK1/RPS6KA1 (NP_002944.2).
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
6195
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using p90Rsk/RSK1/RPS6KA1 Rabbit pAb (CAB15718) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
