The p70 S6 Kinase Rabbit Monoclonal Antibody (CAB4898) is a valuable tool for researchers studying the p70 S6 Kinase protein, a key regulator of cell growth and protein synthesis. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the p70 S6 Kinase protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in cell signaling, cancer research, and drug development.The p70 S6 Kinase protein is a crucial component of the PI3K/Akt/mTOR signaling pathway, which plays a central role in regulating cell proliferation, survival, and metabolism.
Dysregulation of this pathway is commonly implicated in diseases such as cancer, diabetes, and neurological disorders. By targeting the p70 S6 Kinase protein, researchers can gain insights into the molecular mechanisms underlying these diseases and develop novel therapeutic strategies aimed at restoring normal cellular function.Overall, the p70 S6 Kinase Rabbit Monoclonal Antibody (CAB4898) is a reliable reagent for investigating the role of p70 S6 Kinase in physiological and pathological processes, paving the way for advancements in biomedical research and the development of targeted therapies.
Product Name:
p70 S6 Kinase 1 Rabbit Monoclonal Antibody
SKU:
CAB4898
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p70 S6 Kinase 1 (NP_003152.1).
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
6198
Clone Number:
ARC57223
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using p70 S6 Kinase 1 Rabbit mAb (CAB4898) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
