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p70 S6 Kinase 1 Rabbit Monoclonal Antibody (CAB4898)

SKU:
CAB4898
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:p70 S6 Kinase 1 Rabbit Monoclonal Antibody
SKU:CAB4898
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p70 S6 Kinase 1 (NP_003152.1).
Sequence:MRRR RRRD GFYP APDF RDRE AEDM AGVF DIDL DQPE DAGS EDEL EEGG QLNE SMDH GGVG PYEL GMEH CEKF EISE TSVN RGPE KIRP ECFE LLRV LGKG
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha; p70 S6 Kinase 1
Positive Sample:HeLa,293T,Jurkat,Mouse brain,Mouse thymus
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cytoplasm, Mitochondrion outer membrane, Mitochondrion, Nucleus, synapse, synaptosome.
Calculated MW:59kDa
Observed MW:68kDa/75kDa

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Purification Method:Affinity purification
Gene ID:6198
Clone Number:ARC57223
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using p70 S6 Kinase 1 Rabbit mAb (CAB4898) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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